Ocular myasthenia gravis after D-penicillamine administration.
نویسندگان
چکیده
A 68-year-old black woman who was put on D-penicillamine therapy (250-500 mg per day, total dose 15 g) for rheumatoid arthritis developed ocular myasthenia gravis. Two weeks after she discontinued D-penicillamine her signs and symptoms cleared with no other treatment. Review of previous cases and possible immunological mechanisms are discussed.
منابع مشابه
D-Penicillamine induced myasthenia gravis.
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Rheumatoid arthritis can be a very mutilating disease and, as a result, the likelihood of patients with rheumatoid arthritis requiring surgery and anaesthesia is increased. D-penicillamine (D-Pen) has been used in the treatment of rheumatoid arthritis and Wilson's disease since the early 1960s. Its true mode of action is unknown, but it appears to modify the immune response. Treatment with D-Pe...
متن کاملD-penicillamine induced myasthenia gravis. Its relevance for the anaesthetist.
The case of a 57-year-old woman with rheumatoid arthritis is presented to illustrate the rare occurrence of a myasthenic syndrome induced by D-penicillamine, which led to prolonged (5.25-h) postoperative apnoea necessitating artificial ventilation.
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ورودعنوان ژورنال:
- The British journal of ophthalmology
دوره 73 12 شماره
صفحات -
تاریخ انتشار 1989